TY - JOUR AU - Florica Șandru AU - M. Dumitrașcu AU - Cezara Teodorescu AU - Raluca Miulescu AU - Aida Petca AU - Adelina Popa PY - 2020/01/25 Y2 - 2024/03/29 TI - VULVAR MELANOMA – THERAPEUTIC CONSIDERATIONS JF - Romanian Journal of Clinical Research JA - rjcr VL - 3 IS - 1 SE - Articles DO - 10.33695/rjcr.v3i1.45 UR - https://rjcronline.com/index.php/rjcr/article/view/45 AB - Melanoma can develop both on the skin and in the mucosa at different levels: respiratory, gastrointestinal or genital, due to the melanocyte content of these tissues. In most cases, the prognosis of melanoma at the mucosal level has a much worse prognosis compared to that for melanoma at the tegument level. Symptoms described by patients with vulvar melanoma include bleeding, itching, vaginal discharge, dyspareunia or a palpable / visible tumor formation. We present the case of a 56-year-old, presented to our service with macula about 3.5 cm in diameter, dark brown color, and irregular edges, located at the level of the upper pole of the vulva. ER -